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Souren Mkrtchian Selected Research

(5- chloro- 1H- indol- 2- yl)(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)methanone

10/2013CYP2W1 polymorphism: functional aspects and relation to risk for colorectal cancer.
6/2013Colon cancer-specific cytochrome P450 2W1 converts duocarmycin analogues into potent tumor cytotoxins.

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Souren Mkrtchian Research Topics

Disease

8Neoplasms (Cancer)
02/2016 - 10/2006
6Hypoxia (Hypoxemia)
01/2018 - 12/2010
5Inflammation (Inflammations)
10/2021 - 08/2012
5Hepatocellular Carcinoma (Hepatoma)
01/2017 - 05/2010
5Colonic Neoplasms (Colon Cancer)
02/2016 - 10/2007
3Cognitive Dysfunction
01/2021 - 01/2020
3Liver Diseases (Liver Disease)
01/2017 - 01/2016
2Heart Failure
01/2021 - 08/2007
2Infections
01/2020 - 02/2009
2Colorectal Neoplasms (Colorectal Cancer)
01/2015 - 12/2010
1Sleep Apnea Syndromes (Sleep Apnea)
12/2021
1Obstructive Sleep Apnea
12/2021
1Amyloidosis
01/2021
1Non-alcoholic Fatty Liver Disease
01/2018
1Drug-Related Side Effects and Adverse Reactions
01/2018
1Reperfusion Injury
01/2018
1Cholestasis
01/2018
1Hypercapnia
10/2016
1Rhabdomyosarcoma
01/2016
1Adrenocortical Carcinoma
01/2016
1Breast Neoplasms (Breast Cancer)
01/2016
1Type 2 Diabetes Mellitus (MODY)
06/2015
1Respiratory Insufficiency (Respiratory Failure)
12/2010
1Heart Diseases (Heart Disease)
08/2007
1Coronary Disease (Coronary Heart Disease)
08/2007

Drug/Important Bio-Agent (IBA)

6Pharmaceutical PreparationsIBA
01/2018 - 10/2007
4Biomarkers (Surrogate Marker)IBA
12/2021 - 01/2020
4Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
02/2016 - 12/2010
4EnzymesIBA
02/2016 - 10/2007
4ProdrugsIBA
01/2016 - 12/2010
4DuocarmycinsIBA
01/2015 - 06/2013
3MicroRNAs (MicroRNA)IBA
01/2018 - 01/2017
2Biological ProductsIBA
01/2018 - 01/2017
2CalciumIBA
01/2018 - 08/2007
2Oxygen (Dioxygen)IBA
01/2017 - 08/2012
2Proteins (Proteins, Gene)FDA Link
01/2016 - 10/2007
2CytokinesIBA
01/2015 - 08/2014
2Adenosine Triphosphate (ATP)IBA
01/2015 - 08/2014
2(5- chloro- 1H- indol- 2- yl)(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)methanoneIBA
10/2013 - 06/2013
2Cytochrome P-450 CYP2C19IBA
11/2010 - 05/2010
2LuciferasesIBA
11/2010 - 05/2010
1RNA (Ribonucleic Acid)IBA
12/2021
1Calcium-Regulating Hormones and AgentsIBA
01/2021
1Glial Fibrillary Acidic ProteinIBA
01/2020
1Serum AlbuminIBA
01/2020
1Pathogen-Associated Molecular Pattern MoleculesIBA
01/2020
1Propofol (Diprivan)FDA LinkGeneric
10/2016
1DexmedetomidineFDA Link
10/2016
1Vitamin A (Retinol)FDA LinkGeneric
01/2016
1Imatinib Mesylate (Gleevec)FDA Link
01/2015
1Interleukin-10 (Interleukin 10)IBA
08/2014
1InterleukinsIBA
08/2014
1Interleukin-6 (Interleukin 6)IBA
08/2014
1Cytokine Receptors (Cytokine Receptor)IBA
08/2014
1Interleukin-8 (Interleukin 8)IBA
08/2014
1Acetylcholine (Acetylcholine Chloride)FDA Link
08/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
08/2014
1Interleukin-4 (Interleukin 4)IBA
08/2014
1cyclopropapyrroloindoleIBA
08/2013
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
08/2013
1Mixed Function Oxygenases (Monooxygenases)IBA
06/2013
1Histones (Histone)IBA
06/2013
1Cytotoxins (Cytolysins)IBA
06/2013
1(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)(5- fluoro- 1H- indol- 2- yl)methanoneIBA
06/2013
1Raloxifene Hydrochloride (Evista)FDA Link
07/2011
1LigandsIBA
07/2011
1afimoxifene (hydroxytamoxifen)IBA
07/2011
1Neuromuscular Blocking AgentsIBA
12/2010
1AntibodiesIBA
12/2010
1General AnestheticsIBA
12/2010
1Transcription Factors (Transcription Factor)IBA
05/2010
1Alanine (L-Alanine)FDA Link
02/2009
1Lysine (L-Lysine)FDA Link
02/2009
1Messenger RNA (mRNA)IBA
10/2007
1Phosphates (Orthophosphate)IBA
08/2007
1Parathyroid Hormone (Parathormone)IBA
08/2007
1Peptide Hormones (Polypeptide Hormones)IBA
08/2007
1Parathyroid Hormone-Related ProteinIBA
08/2007
1PotassiumIBA
08/2007
1SodiumIBA
08/2007
1Heat-Shock Proteins (Heat-Shock Protein)IBA
10/2006

Therapy/Procedure

5Therapeutics
01/2017 - 10/2007
2Drug Therapy (Chemotherapy)
06/2015 - 06/2013
1Continuous Positive Airway Pressure
12/2021
1Orthopedic Procedures
01/2021
1Anesthesia
12/2010